Among several theories that explain the mechanism of aging, the non-genetic free radical theory of aging is one of the most attractive， because some of the aspects can be explained experimentally. This theory states that most changes during aging are caused by free radical reactions and the formation of lipid peroxides in living tissues, which lead to age-related damage and eventually to various aging processes and phenomena．In order to well understand antiaging, the advance in the studies of the cause, consecuence, and the way of prevention of aging will be learned medically, biochemically, physiologically, and phathologically in this lecture.