Medicinal Chemistry and Organic Synthesis/Exercise1

To understand synthetic medicinal chemistry, synthesis of compounds library and evaluation of their biological activities will be examined. Based on those findings and the pharmacophore analysis, compounds possess more potent activity will be designed.

1. To acquire knowledge and skills of designing and synthesis of functional molecules based on biologically active substances.
2. To understand the structure activity relationship of biologically active compounds and the influence on the living body at the gene or cell level.
3. Understanding of the design of biologically active molecules.

Japanese

Biologically active compounds will be synthesized. For these compound groups, evaluation of biological activity will be carried out using cells and the activity correlation will be also examined. Pharmacophore analysis is carried out based on these information, and a compound having strong physiological activity is designed.

progress situation and attitude for the research

References: Top Drug karamanabu Souyakukagaku by Yukigoseikagakukyokai (Tokyokagakudojin)
Souyaku-Yukigosei karano approach- by Yasuyuki Kita and Tetsuo Hiraoka (Tokyokagakudojin)

Read textbooks

• Thursday, Friday from 1 PM to 5 PM

Environment-related course (10%)

Non-regionally-oriented course

• Course that cultivates an ability for utilizing knowledge

Most classes are interactive