Course title
3M821500,7M4100001
Organic Stereochemistry

 kitagawa osamu Click to show questionnaire result at 2018
Course content
In chiral drugs, biological activities between the enantiomers often significantly differ . Thus, in modern organic chemistry, knowledges of stereochemistry are very important. In this class, I would like to explain in detail on organic stereochemistry．
Purpose of class
Understanding on basic keywords for organic stereochemistry, various chiral compounds and the depiction of the configurations, importance of chiral switch in chiral medical drug
Goals and objectives
  1. Understanding on basic keywords for organic stereochemistry (enantiomer, diastereomer, optically active, meso, conformations, configurations etc).
  2. Understanding on depiction of configurations in enantiomers and diastereomers
  3. Understanding on stereoselective synthesis and resolution method of enantiomers and diastereomers
  4. Understanding on conformation of acyclic and cyclic compounds
Language
English
Class schedule

 Class schedule HW assignments (Including preparation and review of the class.) Amount of Time Required
1． Introduction (Importance of stereochemistry) and confirmation of learning level for student Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
2． Outline of organic stereochemistry Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
3． chiral compounds and their description Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
4． On enantiomer, optically active and racemate Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
5． Diastereomers and meso-compounds Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
6． Chiral compounds having no chiral center Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
7． Diastereoselective synthesis Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
8． Enantioselective synthesis Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
9． Separation of enantiomers (optical resolution) Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
10． Enantiomer enrichmentBi Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
11． Biology and chirality Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
12． Chiral drugs Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
13． On conformation Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
14． Conformation of acyclic and cyclic compounds Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
Total. - - 2800minutes
Relationship between 'Goals and Objectives' and 'Course Outcomes'

 report Total.
1. 25% 25%
2. 25% 25%
3. 25% 25%
4. 25% 25%
Total. 100% -
Evaluation method and criteria
The credit requires over 60% of total scores on the reports of which include the topics of goals and the objectives.
Textbooks and reference materials
Prints will be distributed
Prerequisites
Knowledge of basic organic chemistry (freshman level) may be required.
Office hours and How to contact professors for questions
  • Wednesday pm 2:00 - pm 4:00
Relation to the environment
Regionally-oriented
Development of social and professional independence
    Active-learning course
    Course by professor with work experience
    Work experience Work experience and relevance to the course content if applicatable
    N/A N/A
    Last modified : Thu Mar 21 15:37:34 JST 2019