Course title
6M0059001
Medicinal Chemistry and Organic Synthesis

 suhara yoshitomo Click to show questionnaire result at 2018
Course content
This class provided topics in research area of Pharmaceutical Synthetic Chemistry, Bioorganic and Synthetic Chemistry and Functional Molecular Sciences, which are important for research and development of medicine.
Purpose of class
Understanding of pharmaceutical synthetic chemistry as well as the topics of research field of medicinal chemistry.
Goals and objectives
  1. To understand Pharmaceutical Synthetic Chemistry, Bioorganic and Synthetic Chemistry and Functional Molecular Sciences.
  2. To understand synthetic methods for the total synthesis of organic compounds.
  3. To understand methods for separation and analysis of enantiomers and determination of stereochemistry.
Language
Japanese
Class schedule

 Class schedule HW assignments (Including preparation and review of the class.) Amount of Time Required
1． History of drugs and drug companies Review prints and write a report. 120minutes
Next learning preparation 60minutes
2． Classification of drugs derived from natural products and their restosynthesis I Review prints and write a report. 120minutes
Next learning preparation 60minutes
3． lassification of drugs derived from natural products and their restosynthesis II Review prints and write a report. 120minutes
Next learning preparation 60minutes
4． Carbohydrates and amino acids Review prints and write a report. 120minutes
Next learning preparation 60minutes
5． Heterocyclic compounds Review prints and write a report. 120minutes
Next learning preparation 60minutes
6． Protective groups Review prints and write a report. 120minutes
Next learning preparation 60minutes
7． Organic synthesis utilized organic metals Review prints and write a report. 120minutes
Next learning preparation 60minutes
8． Methods of separation of enantiomer Review prints and write a report. 120minutes
Next learning preparation 60minutes
9． Asymmetric syntheses Review prints and write a report. 120minutes
Next learning preparation 60minutes
10． Mechanism of activity of biologically active agents Review prints and write a report. 120minutes
Next learning preparation 60minutes
11． Structure analyses of receptors and enzymes Review prints and write a report. 120minutes
Next learning preparation 60minutes
12． Interaction between proteins and small molecules Review prints and write a report. 120minutes
Next learning preparation 60minutes
13． Synthesis of small molecules Review prints and write a report. 120minutes
Next learning preparation 60minutes
14． Mechanism of actions of small molecules Review prints and write a report. 120minutes
Total. - - 2460minutes
Relationship between 'Goals and Objectives' and 'Course Outcomes'

 report including mini test Total.
1. 20% 10% 30%
2. 20% 15% 35%
3. 20% 15% 35%
Total. 60% 40% -
Evaluation method and criteria
Class attendance and attitude for the lecture (40%) and report (60%).
Textbooks and reference materials
References: Top Drug karamanabu Souyakukagaku by Yukigoseikagakukyokai (Tokyokagakudojin)
Souyaku-Yukigosei karano approach- by Yasuyuki Kita and Tetsuo Hiraoka (Tokyokagakudojin)
Originally printed-out texts according to the topics will be provided.
Prerequisites
Reading textbooks of medicinal chemistry are recommended to attend to this class.
Office hours and How to contact professors for questions
  • Tuesday and Wednesday PM1:00~5:00
Regionally-oriented
Non-regionally-oriented course
Development of social and professional independence
  • Course that cultivates a basic problem-solving skills
Active-learning course
About half of the classes are interactive
Course by professor with work experience
Work experience Work experience and relevance to the course content if applicatable
N/A N/A
Education related SDGs:the Sustainable Development Goals
  • 4.QUALITY EDUCATION
  • 9.INDUSTRY, INNOVATION AND INFRASTRUCTURE
Last modified : Sat Mar 21 13:14:43 JST 2020