Biophysics is the study of biological systems and biological processes using physics-based methods or based on physical principles.This
course introduces the use of physical methods in the study of biological systems, including macromolecules, membranes, and
nerves. The biological systems to which the methods are applied will be surveyed and current interpretations of their structure
and function will be discussed, based on physical principles.The treatment of biological phenomena will be based on physical
principles with appropriate mathematics when necessary. The emphasis will be on the applications of physics in biology.
To understand at a fundamental level the structure, dynamics, interactions, and ultimately the function of biological systems.
The undergraduate major in biophysics is a great choice for students who enjoy math and physics but are interested in problems
related to biology or medicine.
| Goals and objectives | Course Outcomes | |
|---|---|---|
| 1. | Students will be able to study selected biological phenomena using physical principles. |
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| 2. | Students will be able to achieve true integration among biology, chemistry, physics, and mathematics, and become competent in all these areas. |
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| 3. | Students will be able to obtain the skills and technical abilities to address biological problems at hand |
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| Class schedule | HW assignments (Including preparation and review of the class.) | Amount of Time Required | |
|---|---|---|---|
| 1. | Molecular structure of biological systems Properties of atomic orbitals Intramolecular bonds Intermolecular bonds |
Read Power point presentation and textbook | 300分 |
| Work on exercises | 100分 | ||
| 2. | Absorbtion and emission of light Molecular electronic transtitions Absorption spectrscopy, Raman spectroscopy Fluorescence spectroscopy | Read Power point presentation and textbook | 240分 |
| Work on exercises | 120分 | ||
| 3. | The building blocks Proteins, Lipids, Nucleic acids, Carbohydrates Cell Membrane structure, Cell organelles | Read Power point presentation and textbook | 340分 |
| Work on exercises | 60分 | ||
| 4. | Energy pathways in biology ATP synthesis, photosynthesis Thermodynamics, Functions of state, Enthalpy The fisrt and the second law of thermodynamics | Read Power point presentation and textbook | 340分 |
| Work on exercises | 60分 | ||
| 5. | Transport phenomena The diffusion potential, The second law of
Fick Thermal conductivity, Viscosity Electrical charge transport |
Read Power point presentation and textbook | 340分 |
| Work on exercises | 60分 | ||
| 6. | Enthropy and stability, Osmotic pressure Electrochemical equilibrium - The Nernst Equation The Donnan equilibrium |
Read Power point presentation and textbook | 340分 |
| Work on exercises | 60分 | ||
| 7. | Mid-term exam and discussion on the solutions afterwards | Preparation for mid-term | 400分 |
| 8. | Water The electrostatic potential in electrolytes, The hydrophobic effect, Hydrophobic matching and protein function, Pore formation |
Read Power point presentation and textbook | 340分 |
| Work on exercises | 60分 | ||
| 9. | Separation techniques Chromatography Electrophoresis | Read Power point presentation and textbook | 340分 |
| Work on exercises | 60分 | ||
| 10. | Nerve pulse propagation The Hodgkin–Huxley Model, The role of channels
and pumps, The biophysics of the synapse Two cases: muscle and retina |
Read Power point presentation and textbook | 340分 |
| Work on exercises | 60分 | ||
| 11. | Physical factors of the environment Temperature, Pressure, Mechanical oscillations, Vibration, Sound, Ultrasound | Read Power point presentation and textbook | 340分 |
| Work on exercises | 60分 | ||
| 12. | Static and electromagnetic fields Electromagnetic fields in the human environment Biological effects of electromagnetic fields | Read Power point presentation and textbook | 340分 |
| Work on exercises | 60分 | ||
| 13. | Ionizing radiation Measurement of radioactivity, Biological effects of radiation, Application of radio isotopes | Read Power point presentation and textbook | 320分 |
| Work on exercises | 60分 | ||
| 14. | Final examination and discussion on the course | Preparation for Final examination | 400分 |
| Total. | - | - | 5540分 |
| Midterm,quiz, presentation | Final | Total. | |
|---|---|---|---|
| 1. | 10% | 20% | 30% |
| 2. | 15% | 20% | 35% |
| 3. | 5% | 15% | 20% |
| 4. | 5% | 10% | 15% |
| Total. | 35% | 65% | - |
Mid-term exam, quiz, presentation on exercises etc. will contribute 35% of your grade.
Final exam will contribute 65% of your grade.
Those who get at least 60% of the full score will pass this course.
Final exam will contribute 65% of your grade.
Those who get at least 60% of the full score will pass this course.
Biophysics, R. Glaser, Springer- Verlag Berlin Heidelberg
M. B. Jackson, “Molecular and Cellular Biophysics”, Cambridge University Press, 2006
- Students are asked to contact through email and make appointments. Email:uma@shibaura-it.ac.jp
- Course that cultivates a basic problem-solving skills
| Work experience | Work experience and relevance to the course content if applicatable |
|---|---|
| N/A | N/A |
Last modified : Fri May 15 04:03:30 JST 2020