Developmental genetics is a study that understands how the developmental process of life (individuals) is controlled by genes.
In this lesson, the basics of genetics necessary to understand developmental genetics are explained.
Next, the process of animal development starting from fertilization is explained by using various animals as examples.
Regulation mechanism of animal development by gene expression is explained.
In addition, abnormalities in humans at the developmental stages and the resulting diseases and their diagnosis are explained.
[Notes] Please note that if there are many applicants, students may be determined by lottery.
In this lesson, the basics of genetics necessary to understand developmental genetics are explained.
Next, the process of animal development starting from fertilization is explained by using various animals as examples.
Regulation mechanism of animal development by gene expression is explained.
In addition, abnormalities in humans at the developmental stages and the resulting diseases and their diagnosis are explained.
[Notes] Please note that if there are many applicants, students may be determined by lottery.
In order to understand and study life science, it is necessary to understand how life is developed and what kind of system
is used to develop individuals based on the functions of genes. The purpose of this lesson is to learn the ontogeny of animals
while incorporating knowledge of genetics.
First, you will learn the basics of genetics to understand the function of genes. This study will give you the basic knowledge to learn the role of genes in ontogeny.
Since the early stages of ontogeny starting from fertilization are very unique and strategic, you focus on learning this step.
Individuals developed from a single fertilized egg are differentiated to various organs. You will learn about the mechanism of organ differentiation and the various genes involved.
In the developmental stages, sometimes abnormal development is occurred. You learn about such occurrence abnormality including the cause.
Developmental abnormalities also occur in humans. You will learn them in medicals and how to diagnose them.
First, you will learn the basics of genetics to understand the function of genes. This study will give you the basic knowledge to learn the role of genes in ontogeny.
Since the early stages of ontogeny starting from fertilization are very unique and strategic, you focus on learning this step.
Individuals developed from a single fertilized egg are differentiated to various organs. You will learn about the mechanism of organ differentiation and the various genes involved.
In the developmental stages, sometimes abnormal development is occurred. You learn about such occurrence abnormality including the cause.
Developmental abnormalities also occur in humans. You will learn them in medicals and how to diagnose them.
- Understand the basics of genetics
- Understand the stage of early development from fertilization based on morphology and molecular biology
- Understand the development of the body during ontogenesis, including its molecular mechanism
- Understand the expression regulation mechanism of genes that regulate ontogeny
- Understand abnormalities and related medical treatment
| Class schedule | HW assignments (Including preparation and review of the class.) | Amount of Time Required | |
|---|---|---|---|
| 1. | What is developmental genetics? | Summarize and understand the outline of developmental genetics | 40minutes |
| Summarize and understand the mechanism of genetics | 30minutes | ||
| Summarize and understand the functions of genes that regulate inheritance | 30minutes | ||
| 2. | Fertilization and cleavage / early development | Summarize and understand the path from gametogenesis to fertilization | 40minutes |
| Summarize and understand various cleavage formulas for fertilized eggs | 30minutes | ||
| Summarize and understand the early stages of development after cleavage | 30minutes | ||
| 3. | Various animal development | Summarize and understand various forms of animal development, including vertebrates and insects | 40minutes |
| Summarize and understand the developmental patterns of each organ of the animal using model animals | 30minutes | ||
| Summarize and understand the various molecular mechanisms of development | 30minutes | ||
| 4. | Organ development | Summarize and understand differentiation from early development to endoderm, mesoderm and ectoderm | 40minutes |
| Summarize and understand the differentiation of endoderm, mesoderm and ectoderm into each organ | 30minutes | ||
| Summarize and understand human embryonic development | 30minutes | ||
| 5. | Neural crest cell development | Summarize and understand vertebrate-specific neural crest cell differentiation | 40minutes |
| Summarize and understand various cells and organs differentiated from neural crest cells | 30minutes | ||
| Summarize and understand pigment cells derived from neural crest cells | 30minutes | ||
| 6. | Differential gene expression in development | Summarize and understand the genes that are important for embryonic development | 40minutes |
| Summarize and understand the mechanism of gene expression regulation during embryonic development | 30minutes | ||
| Summarize and understand the differences in gene expression reguration mechanisms between animal species | 30minutes | ||
| 7. | Intermediate examination and commentary | Summary of lecture 1 to 6 | 725minutes |
| 8. | Intercellular communication in development | Summarize and understand the induction signals in embryonic development | 40minutes |
| Summarize and understand cell-cell interactions during embryonic development | 30minutes | ||
| Summarize and understand the signaling pathways required for embryonic development | 30minutes | ||
| 9. | Embryonic limb development | Summarize and understand morphological changes in vertebrate limb development | 40minutes |
| Summarize and understand genes important for limb development | 30minutes | ||
| Summarize and understand limb development and apoptosis | 30minutes | ||
| 10. | Sex determination | Summarize and understand factors for sex determination | 40minutes |
| Summarize and understand the timing of sex determination | 30minutes | ||
| Summarize and understand genes important for sex determination | 30minutes | ||
| 11. | Metamorphosis, regeneration and aging | Summarize and understand animal metamorphosis | 40minutes |
| Summarize and understand animal reproduction | 30minutes | ||
| Summarize and understand animal aging | 30minutes | ||
| 12. | Developmental abnormalities and diseases | Summarize and understand the abnormalities | 40minutes |
| Summarize and understand the causes of abnormalities | 30minutes | ||
| Summarize and understand the mechanisms of developmental abnormalities | 30minutes | ||
| 13. | Embryology and medical care | Summarize and understand various medical treatments for developmental abnormalities | 40minutes |
| Summarize and understand genetic testing and prenatal diagnosis | 30minutes | ||
| Summarize and understand medical technologies using embryology | 30minutes | ||
| 14. | Final exam and commentary | Summary of lecture 8 to13 | 725minutes |
| Total. | - | - | 2650minutes |
| Intermediate exam | Final exam | Mini test | Total. | |
|---|---|---|---|---|
| 1. | 20% | 4% | 24% | |
| 2. | 10% | 4% | 14% | |
| 3. | 10% | 10% | 4% | 24% |
| 4. | 20% | 4% | 24% | |
| 5. | 10% | 4% | 14% | |
| Total. | 40% | 40% | 20% | - |
Grades are evaluated based on the results of 40% for the middle exam, 40% for the final exam and 20% for the mini test. A
total score of 60% or more means passed. The exam covers printed documents, additional documents, lecture notes and oral comments.
You could get 80% in the exam, if you fully understand the content of the lecture.
Textbooks is not used.
Lecture materials should be downloaded from the appropriate class item on Scomb, printed in advance, and attended.
Please bring a device that can access Scomb for each lecture because quizzes conducted in each class use the Scomb system.
Lecture materials should be downloaded from the appropriate class item on Scomb, printed in advance, and attended.
Please bring a device that can access Scomb for each lecture because quizzes conducted in each class use the Scomb system.
- I will respond in the lab from 12:30 to 13:00 on Tuesday and Thursday. It is necessary to contact by email in advance.
- Course that cultivates an ability for utilizing knowledge
- Course that cultivates a basic self-management skills
- Course that cultivates a basic problem-solving skills
| Work experience | Work experience and relevance to the course content if applicatable |
|---|---|
| N/A | N/A |
- 3.GOOD HEALTH AND WELL-BEING
- 4.QUALITY EDUCATION
- 9.INDUSTRY, INNOVATION AND INFRASTRUCTURE
Last modified : Fri Aug 07 04:07:14 JST 2020