Course title
M01530003
Biophotonics

rajagopalan umamaheswari

aaryashree
Course description
The course will present different biosensing technologies with main focus paid to optical technologies. The course will also introduce the students to magnetic resonance imaging (MRI), ultrasound, x-ray imaging, PET and other latest technologies in wide use. As basis of optical sensing technology, the students will be revised of the light properties and their interaction with biological matter. They will be introduced to the basic properties of light such as reflection, refraction, scattering and absorption with emphasis on the scattering properties that include Rayleigh and Mie scattering. Students will be introduced to common microscopes and their limitations, development of super-resolution optical microscopes including NSOM (near-field scanning optical microscope) STED (Stimulated emission depletion), Light sheet microscope and so on. The course will also cover other technologies such as OCT (Optical Coherence Tomography), optical interferometric techniques, opto-genetics, Raman imaging and cutting edge technologies that are under research and also commercially used. By the end of the course, the students should get an idea of how the biologicals systems could be investigated from molecular level to system level and the challenges involved.
Purpose of class
The course is meant for students who are interested in the technologies employed in investigating biological systems and understand the principle of different technologies. Students who have prior knowledge of optical physics principles will find it easier as all the technologies are based on different optical phenomena.
Goals and objectives

Goals and objectives Course Outcomes
1. Students will get to know different technologies magnetic resonance imaging (MRI), ultrasound, x-ray imaging, PET, chromatography and so on.
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2. Students will be able to understand the principle behind the different technologies.
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3. Students will obtain knowledge on implementation of different technologies.
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4. Students will be able not only to understand different technologies but also appreciate the uniqueness and limitations of different technologies.
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5. Student will be able to employ their theoretical knowledge of technologies and get on hands on experience with the instruments in technoplaza
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Language
English
Class schedule

Class schedule HW assignments (Including preparation and review of the class.) Amount of Time Required
1. Optical sensing (understand the basic nature of light; geometrical optics) Prepare for Quiz 10分
Provide class material on scomb page 90分
Assignment 90分
2. Optical sensing ( geometrical optics and wave optics) Prepare for Quiz 10分
Provide class material on scomb page 90分
Assignment 90分
3. Optical sensing (diffraction, interference, scattering, and absorption) Prepare for Quiz 10分
Provide class material on scomb page 90分
Assignment 90分
4. Summary of Optical phenomena Prepare for Quiz 10分
Provide class material on scomb page 100分
Assignment 90分
5. Magnetic resonance imaging, PET and other technologies Prepare for Quiz 10分
Provide class material on scomb page 100分
Assignment 80分
6. Mid-term exam followed by discussion Preparation for exam 180分
7. Introduction to Technoplaza and have a visit to see the different instruments Prepare for Quiz 10分
Provide class material on scomb page 100分
Assignment 90分
8. Cutting edge technologies, (optogenetics, hyperspectral imaging, Raman imaging) Prepare for Quiz 10分
Provide class material on scomb page 100分
Assignment 90分
9. Cutting edge technologies contd. Prepare for Quiz 10分
Provide class material on scomb page 100分
Assignment 90分
10. Hands on practice at Technoplaza Prepare for Quiz 10分
Provide class material on scomb page 100分
Assignment 90分
11. add here Prepare for Quiz 10分
Provide class material on scomb page 100分
Assignment 90分
12. add here Preparation for Q&A time 30分
Preparation for presentation 130分
Teacher feedback time 10分
13. add here Preparation for Q&A time 30分
Preparation for presentation 130分
Teacher feedback time 10分
14. Feedback and end of semester presentations by students Preparation for Q&A time 30分
Preparation for presentation 130分
Teacher feedback time 10分
Total. - - 2650分
Relationship between 'Goals and Objectives' and 'Course Outcomes'

Quiz Midterm exam Final Total.
1. 3% 7% 10% 20%
2. 3% 7% 10% 20%
3. 3% 7% 10% 20%
4. 3% 7% 10% 20%
5. 3% 7% 10% 20%
Total. 15% 35% 50% -
Evaluation method and criteria
Students will be evaluated based on their scores in inclass quiz, midterm exam and final presentation. Students will be encouraged to choose an instrument that is present at technoplaza and make a presentation explaining the principle of operation, uses and limitations. The final score is evaluated based on in-class quiz (15%), midterm test (35%), and final assignment (50%). Credit will be given only when the score is equal or above 60% out of 100% in total.
Textbooks and reference materials
Will be provided material by the teacher through Scomb for every class.
Prerequisites
Interest in optical technologies and their application to biological systems from micro to system level. Understanding of fundamental optical phenomenon will be useful but not a prerequisite.
Office hours and How to contact professors for questions
  • Students are encouraged to contact through email and make an appointment, email:uma@shibaura-it.ac.jp
Regionally-oriented
Non-regionally-oriented course
Development of social and professional independence
  • Course that cultivates an ability for utilizing knowledge
  • Course that cultivates a basic problem-solving skills
  • Course that cultivates a basic interpersonal skills
  • Course that cultivates a basic self-management skills
Active-learning course
Most classes are interactive
Course by professor with work experience
Work experience Work experience and relevance to the course content if applicable
N/A N/A
Education related SDGs:the Sustainable Development Goals
  • 4.QUALITY EDUCATION
  • 7.AFFORDABLE AND CLEAN ENERGY
  • 8.DECENT WORK AND ECONOMIC GROWTH
  • 13.CLIMATE ACTION
  • 14.LIFE BELOW WATER
  • 15.LIFE ON LAND
Last modified : Sat Sep 04 04:04:00 JST 2021