Course title
Chemical biology

HAMASAKI Keita Click to show questionnaire result at 2018
Course content
Chemical biology is a way of understanding biology as a fusion of organic, inorganic, physical, and analytical chemistry. A broad range of disciplines from biochemistry to chemical biology will be discussed focusing on the background, history, and the methodology of it which contributed to development of chemical biology.
Purpose of class
Understanding about chemical biology with related broad science.
Goals and objectives
  1. Understanding for the elements and the molecule of which participates in the biological systems.
  2. Understanding for the structure and activity relationship of the molecules in the biological systems.
  3. Understanding for the way of maitain the biological system
Class schedule

Class schedule HW assignments (Including preparation and review of the class.) Amount of Time Required
1. The elements and chemicals of biological systems What elements are aboundant in a biological organism?
What are the major chemicals in a biological organism?
2. Amino acids, a monomer that construct proteins structure of proteins Why only L-amino acid is available in protein? How L-amino acids are selected and accumulated in nature. 200minutes
3. The structure of proteins. What determine the structure of the protein? State the definition of primary, secondary, tirtialy and qurtenary structure of the protein 200minutes
4. Folding and denaturing of the protein Folding and denaturing of the protein is reversible process. HOw can you make low egg fron boild egg? 200minutes
5. Purification of the protein, separation by size of the protein, separation by the character of the protein Centrifuge, Ultrafiltration, gel filtration, electrophoresis, chromatography 200minutes
6. Enzyme, mechanism and inhibition Foundations of chemical biology, 46-50 200minutes
7. Summary, te relationship between structure of the protein and the role of the protein What kind of function does protein have? That depend on their structural nanure. 200minutes
8. Enzymes in molecular biology How they works in each roles, DNA polymerase, restriction enzyme (DNAse), Ligase 200minutes
9. Chemistry of virus Virus is not living organism. What molecules construct a virus? 200minutes
10. DNA extruction from the cell and purification How can we adopt the tools that useful for protein purification? 200minutes
11. Vector construction How can we construct the desired vector from host vector and insert DNAs? 200minutes
12. Preparation od insert DNAs How can we prerpare insert DNA from genome or plasmide? 200minutes
13. Evaluation of the vector constructed How can we make a judge, if the constructed vector is eight one or not? 200minutes
14. Transformation, screening of the colony and protein suynthsis How can we select a right colony that might have desired vector? 200minutes
Total. - - 2800minutes
Relationship between 'Goals and Objectives' and 'Course Outcomes'

Presentation Essay Total.
1. 25% 25%
2. 25% 25% 50%
3. 25% 25%
Total. 50% 50% -
Evaluation method and criteria
Presentation: 50%
Essay: 50%
The credit requires over 60% of total scores on the examinations of which include the topics of "goals and the objectives".
Textbooks and reference materials
Essentials of chemical biology, Andrew Miller and Julian Tanner, Willey
Organic chemistry, Inorganic chemistry, Physical chemistry, Analytical chemistry, Biological chemistry
Office hours and How to contact professors for questions
  • 10:00-18:00
Non-regionally-oriented course
Development of social and professional independence
  • Course that cultivates an ability for utilizing knowledge
  • Course that cultivates a basic problem-solving skills
Active-learning course
Most classes are interactive
Course by professor with work experience
Work experience Work experience and relevance to the course content if applicable
Education related SDGs:the Sustainable Development Goals
    Last modified : Fri Mar 18 23:12:48 JST 2022