Course title
D00408001
Organic Reaction Mechanism

 KITAGAWA Osamu Click to show questionnaire result at 2018
Course description
Explanation of organic reactions on the basis of organic electron theory
Explanation of reactivity and selectivity in organic reactions
Purpose of class
Understanding of various organic reactions on the basis of organic electron theory
Improvement of logical thinking ability in organic chemistry
Goals and objectives
  1. Understanding on reaction mechanism and reactivity in nucleophilic substitution reaction of organic halides
  2. Understanding on reaction mechanism and selectivity in elimination reaction
  3. Understanding on selectivity and stereochemistry in addition reaction to alkenes
  4. Understanding on reaction mechanism and reactivity in nucleophilic addition and substitution to carbonyl group
  5. Understanding on mechanism in reaction of aromatic compounds
Language
English
Class schedule

 Class schedule HW assignments (Including preparation and review of the class.) Amount of Time Required
1. Nucleophilic substitution reaction (SN1 and SN2 reactions) Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
2. Nucleophilic substitution reaction (Reactivity of substrates and nucleophiles, and synthetic applications) Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
3. Elimination reaction：E1 and E2 reactions Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
4. Stereochemistry of E2 reactions Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
5. Addition to alkenes（regioselectivity） Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
6. Addition to alkenes（stereospecificity） Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
7. Nucleophilic addition reaction to carbonyl group (addition of carbanion and hydride ion) Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
8. Nucleophilic addition reaction to carbonyl group (addition of alcohols and amines) Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
9. Nucleophilic substitution reaction to carboxylic acid derivatives Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
10. Reactivity and character of aromatic compounds Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
11. Electrophilic substitution of aromatic compounds (regiochemistry） Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
12. Various electrophilic substitution reaction（nitration, halogenation, and Friedel-Crafts reaction） Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
13. Nucleophilic substitution of aromatic compounds and substitution reaction via benzyne Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
14. Term exam and its review Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
Total. - - 2800minutes
Relationship between 'Goals and Objectives' and 'Course Outcomes'

 term exam submission of assignment Total.
1. 20% 2% 22%
2. 15% 2% 17%
3. 15% 2% 17%
4. 15% 2% 17%
5. 25% 2% 27%
Total. 90% 10% -
Evaluation method and criteria
The credit requires over 60% of total scores on the examinations and submission of assignments.
Feedback on exams, assignments, etc.
ways of feedback specific contents about "Other"
Feedback in the class
Textbooks and reference materials
Textbook: Organic Chemistry by McMurry (Ver 9), Ed by J. McMurry
Lecture prints will be also distributed.
Prerequisites
Basic knowledge of organic chemistry will be required.
Office hours and How to contact professors for questions
  • Monday 2:00 pm-4:00 pm
    Wednesday 10:00 am-12:00 am
Regionally-oriented
Non-regionally-oriented course
Development of social and professional independence
  • Non-social and professional independence development course
Active-learning course
More than one class is interactive
Course by professor with work experience
Work experience Work experience and relevance to the course content if applicable
N/A
Education related SDGs:the Sustainable Development Goals
  • 4.QUALITY EDUCATION
Last modified : Thu Feb 22 04:05:30 JST 2024