Course title
3M821500,7M4100001
Organic Stereochemistry

 KITAGAWA Osamu Click to show questionnaire result at 2019
Course content
In chiral drugs, biological activities between the enantiomers often significantly differ . Thus, in modern organic chemistry, knowledges of stereochemistry are very important. In this class, I would like to explain in detail on organic stereochemistry．
Purpose of class
Understanding on basic keywords for organic stereochemistry, various chiral compounds and the depiction of the configurations, importance of chiral switch in chiral medical drug
Goals and objectives
  1. Understanding on basic keywords for organic stereochemistry (enantiomer, diastereomer, optically active, meso, conformations, configurations etc).
  2. Understanding on depiction of configurations in enantiomers and diastereomers
  3. Understanding on conformation of acyclic and cyclic compounds
  4. Understanding on various chiral compounds possessing centrally, axially, planar, helically chiralities
  5. Understanding on stereoselective synthesis and resolution method of enantiomers and diastereomers
Relationship between 'Goals and Objectives' and 'Course Outcomes'

 report Total.
1. 25% 25%
2. 25% 25%
3. 25% 25%
4. 25% 25%
Total. 100% -
Language
English
Class schedule

 Class schedule HW assignments (Including preparation and review of the class.) Amount of Time Required
1． Introduction (Importance of stereochemistry) and confirmation of learning level for student Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
2． Outline of organic stereochemistry Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
3． chiral compounds and their description Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
4． On enantiomer, optically active and racemate Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
5． Diastereomers and meso-compounds Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
6． Chiral compounds having no chiral center Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
7． Conformers of acyclic compounds Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
8． Conformers of cyclic compounds (axial and equatorial bonds) Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
9． Chiral sulfoxide and phophine Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
10． Separation of enantiomers (optical resolution) Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
11． Enantioselective reactions using chiral transition-metal catalysts Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
12． Enantioselective reactions using chiral organocatalysts Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
13． Biology and chirality Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
14． Chiral drugs Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
Total. - - 2800minutes
Evaluation method and criteria
The credit requires over 60% of total scores on the reports of which include the topics of goals and the objectives.
Feedback on exams, assignments, etc.
ways of feedback specific contents about "Other"
Feedback in the class
Textbooks and reference materials
Prints will be distributed
Prerequisites
Knowledge of basic organic chemistry (freshman level) may be required.
Office hours and How to contact professors for questions
  • Monday 9:00 am - 12:00 am
Regionally-oriented
Development of social and professional independence
  • Non-social and professional independence development course
Active-learning course
Most classes are interactive
Course by professor with work experience
Work experience Work experience and relevance to the course content if applicable
N/A N/A
Education related SDGs:the Sustainable Development Goals
  • 4.QUALITY EDUCATION
Last modified : Tue Apr 01 04:05:09 JST 2025