Course title
D00300003
Bioinorganic Chemistry

 HORI Akiko
Course description
In this course, students will first review the basics of elementary "complex chemistry," i.e., electronic configuration and properties of transition metals and their reactions. Next, the knowledge is applied to molecular structures and properties of supramolecular metal complexes and catalysts. Students will also learn the role of metal ions and their applications in artificial models and medicine as they deal with transcription, transport, storage, electron transfer, and enzymes as examples of the use of metal ions in biology.
Purpose of class
To study the role of metal ions in major active sites in living organisms from the basics of complex chemistry, an organic/inorganic hybrid material.
1) To be able to explain the relationship between the structure and physical properties of d-metal complexes.
2) To be able to explain supramolecular metal complexes and catalysts as examples of metal complex applications in terms of structure and function.
3) Understand the roles of major metal ions in the active sites of living organisms and explain their application to pharmaceuticals.
Goals and objectives
  1. To be able to explain the relationship between the structure and physical properties of d-metal complexes.
  2. To be able to explain supramolecular metal complexes and catalysts as examples of metal complex applications in terms of structure and function.
  3. Understand the roles of major metal ions in the active sites of living organisms and explain their application to pharmaceuticals.
Relationship between 'Goals and Objectives' and 'Course Outcomes'

 Quizzes Research study Term-end examination Total.
1. 10% 5% 15% 30%
2. 10% 15% 15% 40%
3. 10% 20% 30%
Total. 30% 20% 50% -
Evaluation method and criteria
Take several quizzes in one semester. A total of 100 points, including 30 points for the quiz, 20 points for the report, and 50 points for the final exam, and a total score of 60 points or more is passed.
A score of approximately 60% is given to the student who can solve the basic exercises and new problems of the same level.
If you master the content of each quiz and can solve it by yourself without referring to textbooks and notebooks, you should be able to score 80% in the final exam.
Language
Japanese
Class schedule

 Class schedule HW assignments (Including preparation and review of the class.) Amount of Time Required
1. Introduction to coordination chemistry diversity of metal complexes, role of organic molecules in metal complexes Read the textbook and complete the assignments. 130minutes
2. d-metal complexes: electronic structure and physical properties crystal field theory, ligand field theory, electronic configuration and structure Read the textbook and complete the assignments. 200minutes
3. d-metal complexes: electronic structure and properties electronic spectra, magnetism Read the textbook and complete the assignments. 200minutes
4. Coordination chemistry: reactions of complexes, ligand substitution reactions, redox reactions, photochemical reactions Read the textbook and complete the assignments. 200minutes
5. Materials chemistry and nanomaterials: terminology and history, nanostructures and properties Read the textbook and complete the assignments. 200minutes
6. Supramolecular metal complexes: molecular interactions, polynuclear metal complexes, coordination polymers Read the textbook and complete the assignments. 200minutes
7. Research studies, and explanation To prepare the report and summarize the applications of familiar metal complexes. 200minutes
8. Catalysts: general principles, homogeneous and heterogeneous catalysts Read the textbook and complete the assignments. 130minutes
9. Inorganic composition of biology: trace elements, metal coordination sites Read the textbook and complete the assignments. 200minutes
10. Transcription, transport, and storage: zinc and oxygen transport and storage in transcription Read the textbook and complete the assignments. 200minutes
11. Electron transfer and enzymes: cytochrome, dinuclear metal complexes, metal clusters Read the textbook and complete the assignments. 200minutes
12. Design and synthesis of metal complexes: artificial models, analytical methods Read the textbook and complete the assignments. 200minutes
13. Inorganic chemistry in medicine: metal complexes used in therapy, chelation therapy Read the textbook and complete the assignments. 200minutes
14. Term-end examination and explanation Review all the contents. 200minutes
Total. - - 2660minutes
Feedback on exams, assignments, etc.
ways of feedback specific contents about "Other"
Feedback in the class
Textbooks and reference materials
Textbooks:
シュライバー・アトキンス無機化学（下）（M. Weller他著、東京化学同人）

Reference books:
　「新しい基礎無機化学」合原　眞 編著（三共出版）
　「基礎無機化学」J.D.Lee / 浜口　博 訳（東京化学同人）

Handouts will be provided through LMS Scomb.
Prerequisites
Students have already taken Chemical Bonding Theory and Inorganic Chemistry 1 and 2.
Office hours and How to contact professors for questions
  • Please contact on Friday from 13:20 to 15:00 at Rm 3100-1 on 1st floor of the 3rd building, or e-mail to ahori@shibaura-it.ac.jp.
Regionally-oriented
Non-regionally-oriented course
Development of social and professional independence
  • Course that cultivates an ability for utilizing knowledge
  • Course that cultivates a basic problem-solving skills
Active-learning course
Most classes are interactive
Course by professor with work experience
Work experience Work experience and relevance to the course content if applicable
N/A 該当しない
Education related SDGs:the Sustainable Development Goals
  • 3.GOOD HEALTH AND WELL-BEING
  • 9.INDUSTRY, INNOVATION AND INFRASTRUCTURE
  • 12.RESPONSIBLE CONSUMPTION & PRODUCTION
Last modified : Thu Mar 06 10:25:25 JST 2025