Course title
D05027002
Biological Chemistry

 YAMASHITA Mitsuo Click to show questionnaire result at 2019
Course description
Fundamental knowledge of biomolecule is understood in organic chemistry, bioorganic chemistry and biochemistry 1. Metabolism and control of biomolecules are understood in biochemistry 2. Metabolism is sum of all enzyme-catalyzed reactions, synthesize and degradation, in a living organism to keep homeostasis.
Purpose of class
The objective is to understand typical metabolic pathways and flows of information from genes to proteins.
Goals and objectives
  1. You are able to comprehend metabolism and control accompanied by life phenomena.
  2. You are able to comprehend synthesis and degradation of energy and bimolecular essential in cells.
  3. You are able to comprehend mechanism of information transfer of the pathways.
Language
English
Class schedule

 Class schedule HW assignments (Including preparation and review of the class.) Amount of Time Required
1. Metabolism: biosynthesis and biodegradation Chapter 4 200minutes
2. Enzyme: reaction mechanism and its control Chapter 2 200minutes
3. Carbohydrate metabolism (1): glycolysis, fermentation, gluconeogenesis Chapter 5 200minutes
4. Carbohydrate metabolism (2): glycogen metabolism, pentose phosphate pathway Chapter 5 200minutes
5. Aerobic metabolism (1): citric acid cycle and its control, electron transport, oxidative phosphorylation, Chapter 4 200minutes
6. Aerobic metabolism (2): electron transport, oxidative phosphorylation, ATP synthesis, photosynthesis Chapter 4 200minutes
7. Lipid metabolism (1): lipid transport, fatty acid oxidation and ketone body Chapter 7 200minutes
8. Lipid metabolism (2): fatty acid and triacylglycerol (TAG) biosynthesis, sterol metabolism Chapter 7 200minutes
9. Nitrogen metabolism (1): amino acids degradation and urea cycle Chapter 8 200minutes
10. Nitrogen metabolism (2): nitrogen metabolism, amino acids biosynthesis, nucleotide metabolism Chapter 8 200minutes
11. Genetic information (1): gene, DNA replication,, nucleotide metabolism Chapter 9 200minutes
12. Genetic information (2): RNA, transcription (synthesis of RNA), expression Chapter 9 200minutes
13. Genetic information (3): genetic code, translation (protein synthesis) Chapter 9 200minutes
14. Final examination Whole text 200minutes
Total. - - 2800minutes
Relationship between 'Goals and Objectives' and 'Course Outcomes'

 Quiz Final examination Total.
1. 7% 30% 37%
2. 7% 30% 37%
3. 6% 20% 26%
Total. 20% 80% -
Evaluation method and criteria
The credit requires over 60% of total score on the examinations of which include the topics of "goals and the objectives".
Textbooks and reference materials
Text book: Fundamentals of General, Organic, and Biological Chemistry (8th Edition)
John McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson Fumio Sugawara and Koji Kuramochi supervisor (Maruzen)
Reference book: Biochemistry: The Molecular Basis of Life Sixth Edition
Trudy McKee, James R. McKee 　Atsushi Ichikawa supervisor, Shinichi Fukuoka chief translator　（Kagakudojin）
Prerequisites
It is important to learn basic knowledge of organic chemistry, organic-biochemistry.
Office hours and How to contact professors for questions
  • Lunch time on every Monday is available for me.
Regionally-oriented
Non-regionally-oriented course
Development of social and professional independence
  • Course that cultivates an ability for utilizing knowledge
  • Course that cultivates a basic problem-solving skills
Active-learning course
More than one class is interactive
Course by professor with work experience
Work experience Work experience and relevance to the course content if applicable
Applicable Applied Chemistry　「Biological Chemistry」（Mitsuo Yamashita Prof.）
Based on a working experience in Pharmaceutical company, I lecture you the metabolism and control of biomolecules.
Education related SDGs:the Sustainable Development Goals
  • 3.GOOD HEALTH AND WELL-BEING
  • 7.AFFORDABLE AND CLEAN ENERGY
Last modified : Fri Mar 18 23:41:48 JST 2022