Course title
D00320003
Synthetic Organic Chemistry

 KIDOWAKI Masatoshi
Course description
Lecture on various organic reactions and reagents
Lecture on the synthetic pathway (retro-synthesis) for preparation of various organic compounds such as organic functional materials
Lecture on the stereospecific reaction
Lecture on the chemistry of amine and heterocyclic compounds
Purpose of class
Many organic compounds such as pharmaceutical chemicals, agricultural chemicals, and electronic materials have been prepared through synthetic organic reactions. The purposes of this class are understanding basic organic reactions, reagents, and retro-synthesis analysis for efficient preparation of various organic compounds.
Goals and objectives
  1. Understanding of basic C-C bond forming reactions (Schedule 1-7)
  2. Understanding of the functionalization of aromatic compounds (Schedule 8-10)
  3. Understanding on the functionalization of various organic compounds through oxidation and reduction (Schedule 11-12)
  4. Understanding of amine and heterocyclic compounds chemistry (Schedule 13)
  5. Understanding of synthetic scheme (Schedule 14)
Relationship between 'Goals and Objectives' and 'Course Outcomes'

 mid-term exam term exam Total.
1. 35% 10% 45%
2. 0% 10% 10%
3. 0% 10% 10%
4. 0% 10% 10%
5. 15% 10% 25%
Total. 50% 50% -
Evaluation method and criteria
The credit requires over 60% of total scores on the examinations of which include the topics of goals and the objectives.
Language
English
Class schedule

 Class schedule HW assignments (Including preparation and review of the class.) Amount of Time Required
1. Significance of synthetic organic chemistry (Contribution to organic material chemistry) Reading of syllabus 200minutes
2. Reaction with Grignard reagents and lithium reagents Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
3. Reaction with organo-cooper lithium reagents and acetylides Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
4. Alkylation with enolate anions and active methine compounds Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
5. Aldol reaction and Michael addition Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
6. Other C-C bond forming reactions with carboanions（Wittig reaction etc） Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
7. Midterm examination and its review Review of midterm exam 200minutes
8. Nitration, halogenation and Friedel-Crafts reaction of aromatic compounds Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
9. Synthesis of various aromatic compounds using electrophilic aromatic substitution reactions Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
10. Synthetic reaction using nucleophilic aromatic substitution and benzyne Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
11. Various oxidation and reduction reactions Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
12. Stereospecific reactions (addition to alkene) Prints for preparation and review of the class will be distributed. Reading of these prints. 200minutes
13. Amine and heterocyclic compounds chemistry Prints for preparation and review of the class will be distributed. Reading of these prints. 230minutes
14. Term exam and its review Review of term exam 200minutes
Total. - - 2830minutes
Feedback on exams, assignments, etc.
ways of feedback specific contents about "Other"
Feedback in the class
Textbooks and reference materials
Textbook: Organic Chemistry by McMurry (Ver 9), Ed by J. McMurry
Lecture prints will be also distributed.
Reference book: "Organic Chemistry" by Stuart Warren
Prerequisites
Basic knowledge of organic chemistry will be required.
Office hours and How to contact professors for questions
  • 11 pm - 15 pm on Thursday.
    It's preferable to contact in advance.
Regionally-oriented
Non-regionally-oriented course
Development of social and professional independence
  • Non-social and professional independence development course
Active-learning course
More than one class is interactive
Course by professor with work experience
Work experience Work experience and relevance to the course content if applicable
N/A N/A
Education related SDGs:the Sustainable Development Goals
  • 9.INDUSTRY, INNOVATION AND INFRASTRUCTURE
Last modified : Sat Mar 08 04:19:34 JST 2025