To acquire fundamental knowledge of the statistical interpretation of analytical data.
To be able to explain the basic principles and overviews of several instrumental analytical methods.
To be able to explain the limitations of analytical methods used by the student.
To be able to explain the basic principles and overviews of several instrumental analytical methods.
To be able to explain the limitations of analytical methods used by the student.
In modern chemical research, measurements using a wide range of instrumental analytical methods are widely employed. Although
recent instruments allow users to obtain data by simply setting samples and applying standard measurement conditions, it is
essential to understand the principles of each analytical technique and to acquire knowledge of data analysis in order to
make full use of the obtained data.
This course first introduces fundamental statistical concepts necessary for the interpretation of analytical data. In particular, students will learn the principles of hypothesis testing commonly encountered in scientific literature and will develop an understanding of the evaluation of measurement uncertainty. Next, several representative instrumental analytical methods are introduced, including their principles, instrument configurations, and the chemical information that can be obtained from the data, with the aim of providing an overview of each technique. Finally, by integrating the statistical interpretation and instrumental analysis covered in the course, an introduction to method validation is provided, and students will conduct an introductory validation of the analytical method used in their own research.
This course first introduces fundamental statistical concepts necessary for the interpretation of analytical data. In particular, students will learn the principles of hypothesis testing commonly encountered in scientific literature and will develop an understanding of the evaluation of measurement uncertainty. Next, several representative instrumental analytical methods are introduced, including their principles, instrument configurations, and the chemical information that can be obtained from the data, with the aim of providing an overview of each technique. Finally, by integrating the statistical interpretation and instrumental analysis covered in the course, an introduction to method validation is provided, and students will conduct an introductory validation of the analytical method used in their own research.
- To understand and apply the statistical interpretation of analytical data, particularly the fundamentals of hypothesis testing and the evaluation of measurement uncertainty.
- To be able to explain the basic principles of various instrumental analytical methods.
- To be able to evaluate the limitations of the analytical methods used in one’s own research.
| Reports and assignments | Total. | |
|---|---|---|
| 1. | 40% | 40% |
| 2. | 40% | 40% |
| 3. | 20% | 20% |
| Total. | 100% | - |
| Class schedule | HW assignments (Including preparation and review of the class.) | Amount of Time Required | |
|---|---|---|---|
| 1． | Analytical Chemistry and Statistics (1) | Learning basic statistical quantities and probability distributions | 200minutes |
| 2． | Analytical Chemistry and Statistics (2) | Learning sample distribution and central limit theorem | 200minutes |
| 3． | Analytical Chemistry and Statistics (3) | Learning hypothesis test, particularly t-test and F-test | 200minutes |
| 4． | Analytical Chemistry and Statistics (4) | Learning hypothesis test, particularly t-test and F-test | 200minutes |
| 5． | Analytical Chemistry and Statistics (5) | Learning how to evaluate measurement uncertainty | 200minutes |
| 6． | Analytical Chemistry and Statistics (6) | Learning multivariate analysis | 200minutes |
| 7． | Instrumental analysis (1) | Learning vibrational spectroscopy | 200minutes |
| 8． | Instrumental analysis (2) | Learning separation analysis | 200minutes |
| 9． | Instrumental analysis (3) | Learning gas chromatography and liquid chromatography | 200minutes |
| 10． | Instrumental analysis (4) | Learning mass spectrometry | 200minutes |
| 11． | Instrumental analysis (5) | Learning X-ray analysis | 200minutes |
| 12． | Validation of method (1) | Learning the idea of validation of method | 200minutes |
| 13． | Analytical chemistry in forensic science | Learning application of analytical chemistry to forensic science | 200minutes |
| 14． | Validation of method (2) | Learning factors affecting measurement uncertainty | 200minutes |
| Total. | - | - | 2800minutes |
Scores from reports and assignments presented as appropriate during the course will be totaled, with a maximum of 100 points.
A total score of 60 points or higher is required to pass the course.
The grading criteria are designed such that students who demonstrate a fundamental understanding of the material explained in class will be able to obtain approximately 60 points.
The grading criteria are designed such that students who demonstrate a fundamental understanding of the material explained in class will be able to obtain approximately 60 points.
| ways of feedback | specific contents about "Other" |
|---|---|
| Feedback outside of the class (ScombZ, mail, etc.) |
Reference materials will be distributed within the lectures.
Reference material books:
機器分析（エキスパート応用化学テキストシリーズ）（講談社, Japanese）
スペクトル定量分析（講談社, Japanese）
ゼロから学ぶ 分析法バリデーション（じほう, Japanese）
Reference material books:
機器分析（エキスパート応用化学テキストシリーズ）（講談社, Japanese）
スペクトル定量分析（講談社, Japanese）
ゼロから学ぶ 分析法バリデーション（じほう, Japanese）
- Office hour: Not specified. Please make an appointment by e-mail.
- Course that cultivates an ability for utilizing knowledge
- Course that cultivates a basic problem-solving skills
| Work experience | Work experience and relevance to the course content if applicable |
|---|---|
| Applicable | The instructor, who has professional experience in forensic analysis using analytical chemistry, teaches the fundamental concepts for the rational interpretation of data obtained through analytical chemistry by drawing on this practical experience. |
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Last modified : Thu Mar 05 16:09:47 JST 2026